IGF-1 LR3 is a synthetic, recombinant analog of human insulin-like growth factor 1 (IGF-1) comprising 83 amino acids. It differs from native IGF-1 by the substitution of Arginine for Glutamic acid at position 3 (R3) and an N-terminal extension of 13 amino acids (Long). These structural modifications significantly reduce its binding affinity for IGF-binding proteins (IGFBPs), thereby enhancing its bioavailability and potency in cell culture studies focused on cellular proliferation, differentiation, and survival.
Key Specifications:
- ICN: 1-0902-0010
- Alias: Long R3 IGF-1
- Strength: 1mg
- CAS Number: 946870-92-4
- Formula: C400H625N111O115S9
- M.W.: 9117.5 g/mol
- Purity: >99%
Storage Instructions:
Store in a cool, dry place at -20°C for long-term storage, or 2-8°C for short-term storage. Protect from light. Reconstituted solutions should be stored under sterile conditions at 2-8°C and used within 28 days.
Disclaimer:
For research use only. Not for human or veterinary use. Not for consumption or therapeutic application.
